Visualizing the next generation of sequencing data with GenomeView .. .. A .. Why inverse proteins are relatively abundant, J.-C. Nebel and C. Walawage, Protein & Peptide Letters, 17(7), Michal Nánási ([email protected] ) Website: (free download, tutorials, manual, . Next generation sequencing presents new challenges in large scale data at the European Conference of Computational Biology (ECCB) , Ghent. Tutorials, workshops and seminars To do bioinformatics well, you need to learn 3 things. ECCB Next-gen sequencing Tutorial (Thomas [email protected]).

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Essentially, these efforts contribute to the success and reputation of the ECCB conference!

Presenters

The annotation of the non-coding genome with gene regulatory function is lagging far behind the annotation of protein-coding genes and improved annotation will depend both on deeper biological insight into cis-regulatory logic and on more efficient computational prediction algorithms. At least sixteen exhibitor booths will be open throughout the conference in the central conference hall, which is well connected to the other activities at ECCB: The 48 accepted papers are included in this special issue.

The origins of problems are discussed as well as their importance for follow up studies. Introduction to short read alignment algorithms and tools Practical instructions and examples on use of short read aligners Parallelising short read alignment Introduction to sequence assembly methods and tools Practical instructions on use of short read assembly tools to get the optimal sequence assembly. In this short course, we will introduce the participants to the different next-generation sequencing technologies, show how to do some basic quality checking of the data, how to run the various next-generation alignment tools, create de novo sequence assemblies, and call variants such as SNPs, short indels, and structural variants from a reference sequence.

This year four different tracks were created for ECCB: Motivation In recent years, there has been a revolution in the area of DNA sequencing with the arrival of next-generation sequencing technologies.

Inhe co-founded the Vertebrate Resequencing Informatics group and manages the sequencing, informatics, and variation pipelines for large projects such as the genomes http: All original research papers that had been published in peer-review journals between 1 March,and the submission deadline of 29 Marchwere eligible to be presented as a Highlight talk.

We also gratefully acknowledge the hard and diligent work performed by the reviewers over a short period of time. Today’s software and CPU time availability on clusters, super computers, and the grid allow for easy improvement of old files. In recent years, there has been a revolution in the area of DNA sequencing with the arrival of next-generation sequencing technologies.

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Next generation sequencing | Taverna

Participants will be provided with an overview of existing resources databases, tools and methods for detecting cis-regulatory elements in genome sequences, and generate testable hypotheses about the binding specificity of transcription factors motifs discoverytheir precise binding locations binding site predictionand their target genes target identificationand go towards regulatory networks.

After the reviewers reached a consensus, a final ranking and selection for each theme was carried out by the theme co- chairs. Computational analysis platforms are challenged by the enormous complexity of biological systems and the sheer amount of data resulting from high-throughput measuring techniques, such as wccb or single-molecule measurements.

Recent data obtained by high-throughput experiments accelerate the genome-wide identification of regulatory elements but also provide additional bioinformatics challenges. We also arranged with FResearch http: The workshops, running all but one for a single day, provide participants with an informal setting to discuss technical issues, exchange research ideas, squencing to share practical experiences on a range of focused or emerging topics in computational biology.

On the scientific side, the Proceedings Track presents novel scientific contributions, while the Highlights Track showcases already published high-impact science in computational biology. We believe that for all of the rejected submissions, the reviewers provided high-quality reports.

Next generation sequencing

It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. We received tutoeial than eighty applications for travel fellowships from young scientists with an oral or poster presentation. First of all, we are indebted to the program committee composed of the theme co- chairs and reviewers for their crucial and dedicated work.

They will be presenting the latest scientific literature in the field of computational biology, bioinformatics, data stewardship, modeling and simulation, as well as new hardware, software and technology developments. In the light of these developments, this tutorial will focus on bioinformatics methods to predict cis-regulatory elements and to aid the process of regulatory annotation. Submissions to this track should cross the boundaries of traditional academic science, or show developments that are directly relevant beyond academia or have potential for it.

The review form explicitly differentiated between impact and suitability for ECCB on the one hand, and scientific quality and reproducibility on the other. It offers participants an opportunity to learn about new areas of bioinformatics research, to get an introduction to important established topics, or to develop advanced skills in areas about which they are already familiar. The ECCB conferences are gathering about a thousand scientists and industry staff working at the intersection of a broad range of disciplines including computer science, mathematics, biology and medicine.

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The aim of this tutorial is to briefly introduce the key basic principles needed to understand what it means to represent information on the Semantic Web, and then to provide the attendees with basic hands on competences to start using biomedical information resources which are now available on this framework. Gkoutos University of Birmingham, UK. Sponsored Talks enable sponsors to showcase their innovations in computational biology and to highlight their scientific value.

Finally, the ELIXIR track proved to be a very popular addition, with 50 high-quality submissions for only 12 presentation slots. His current work includes downstream analysis of next-generation sequencing data in order to identify putative SNPs and indels.

Many people contributed to the local organization of the conference, often much beyond the call of duty, and we owe them a great debt, in particular Femke Francissen and Jacintha van Beemen, both at the Dutch Techcentre for Life Sciences DTL for their relentless logistic and organizational support.

Consequently, submissions relating to pure research were seauencing out of scope. As a consequence, databases and software are evolving rapidly, and new 22010 are required to improve computational analyses of massive biological or biomedical datasets. Recent advances in homology modelling and drug design have made clear that the quality of protein structures is really imnportant for good results.

Flexible and interactive visualization of GFA sequence graphs. Each tutorial will offer participants an opportunity to learn about new areas of bioinformatics research, to get an introduction to important established topics, or to develop advanced skills in areas they are already familiar with. To present a more unified view of where the science has gone over recent years, new to ECCB this year is that the conference presentations are divided over five broad themes: Sign In or Create an Account.

Next-ben reviewing and selection process was carried out using the EasyChair multi-track conference reviewing system www. Jan Aerts received his PhD at Wageningen University Netherlands in on the subject of chicken genome mapping and sequencing. Email alerts New issue alert.